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rasMutations in Endocrine Tumors: Mutation Detection by Polymerase Chain Reaction-Single Strand Conformation Polymorphism

โœ Scribed by Yoshimoto, Katsuhiko ;Iwahana, Hiroyuki ;Fukuda, Ayumi ;Sano, Toshiaki ;Katsuragi, Kiyonori ;Kinoshita, Moritoshi ;Saito, Shiro ;Itakura, Mitsuo


Book ID
108579560
Publisher
Wiley (Blackwell Publishing)
Year
1992
Tongue
English
Weight
386 KB
Volume
83
Category
Article
ISSN
0910-5050

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Analysis of single-stranded conformation polymorphisms in polymerase chain reaction (PCR) products (PCR-SSCP) is a sensitive method for detecting point mutations in genomic DNA. To investigate its utility in examining the androgen receptor gene, we analyzed data on a patient with the testicular femi