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Detection of anti-DNA antibodies in systemic lupus erythematosus (SLE) by counterimmunoelectrophoresis (CIE)

✍ Scribed by BIUNDO, J; SALVAGGIO, J; LOPEZ, M; KOHLER, P

Book ID: 119494353
Publisher: Elsevier Science
Year: 1973
Tongue: English
Weight: 165 KB
Volume: 51
Category: Article
ISSN: 1097-6825
DOI: 10.1016/s0091-6749(73)80051-x

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## Abstract Twenty‐one sera from 11 patients with systemic lupus erythematosus were titrated with ^125^I‐ss‐calf thymus DNA to determine their maximum capacity to bind DNA. Only five sera were capable of binding > 90% of the input DNA. The remaining sixteen sera showed maximum DNA binding levels be