Detection of a monoclonal antibody therapy (ofatumumab) by serum protein and immunofixation electrophoresis
β Scribed by Jonathan R. Genzen; Kathy R. Kawaguchi; Richard R. Furman
- Book ID
- 108677226
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 142 KB
- Volume
- 155
- Category
- Article
- ISSN
- 0007-1048
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## Objectives: To assess the relative value of visual inspection of protein electrophoresis patterns, immunoelectrophoresis, immunofixation, and specific protein quantitation in the investigation of serum proteins. ## Design and methods: A retrospective study of protein results on 372 sera analyz
Rabbit antisera and monoclonal antibodies were raised against factor C, a regulatory protein of Streptomyces griseus. ELISA and immunoblotting techniques suitable to determine and characterize factor C antigen was detected in all the 23 Streptomyces strains and variants examined thus far and in one