Detection and quantitation of human papillomavirus DNA in primary tumour and lymph nodes of patients with early stage cervical carcinoma
β Scribed by Paul K.S. Chan; May M.Y. Yu; Tak-Hong Cheung; Ka-Fai To; Keith W.K. Lo; Jo L.K. Cheung; Joanna H.M. Tong
- Book ID
- 116630758
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 76 KB
- Volume
- 33
- Category
- Article
- ISSN
- 1386-6532
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Human papillomavirus (HPV) 16 is most prevalent in cenical cancers and also persists in metastases. We examined HPV 16-DNA-positive primary cancers and several lymph nodes from each of 14 patients to evaluate the use of HPV16 D N A as a diagnostic marker for the detection of early node involvement.
## Background: The role of human papillomavirus (hpv) as a prognostic factor in cervical carcinoma is not understood completely and little is known regarding the intrinsic mechanisms involved in the metastatic process of hpv positive carcinoma. the authors evaluated hpv status with respect to clini
Seven biopsy specimens from squamous-cell carcinomas of the uterine cervix were examined by RT-PCR for humanpapilloma-virus(HPV)-specific transcripts. With our HPVl8transcription-specific primer pair (5' nts 127-149; 3' nts 587-607), all 7 were shown to contain one strong viral mRNA signal from the