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Detection and determination of certain ureas with o-phthalaldehyde and N-(1-naphthyl)-N′-diethylethylenediamine

✍ Scribed by Tsutomu Momose

Book ID
118993276
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
161 KB
Volume
27
Category
Article
ISSN
0039-9140

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Determination of eflornithine enantiomer
Determination of eflornithine enantiomers in plasma by precolumn derivatization with o-phthalaldehyde-N-acetyl-l-cysteine and liquid chromatography with UV detection
✍ R. Jansson-Löfmark; S. Römsing; E. Albers; M. Ashton 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 363 KB 👁 1 views

## Abstract A bioanalytical method for indirect determination of eflornithine enantiomers in 75 μL human plasma has been developed and validated. l‐ and d‐eflornithine were derivatized with __o__‐phthalaldehyde and __N__‐acetyl‐L‐cysteine to generate diastereomers which were separated on two serial