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Detecting protein complexes based on relevancy from protein interaction networks

✍ Scribed by Yao, Hua-Xiong; Yang, Yan; Li, Xiao-Long

Book ID
121594923
Publisher
International Association of Scientists in the Interdisciplinary Areas
Year
2013
Tongue
English
Weight
777 KB
Volume
5
Category
Article
ISSN
1913-2751

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Spectral clustering for detecting protei
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✍ Guimin Qin; Lin Gao πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 English βš– 416 KB

In this paper, we study spectral clustering for detecting protein complexes in PPI (protein-protein interaction) networks, focusing on two open issues: (i) constructing similarity graphs; and (ii) determining the number of clusters. First, we study four similarity graphs to construct graph Laplacian