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Detecting overlapping protein complexes in protein-protein interaction networks

✍ Scribed by Nepusz, Tamás; Yu, Haiyuan; Paccanaro, Alberto


Book ID
111652692
Publisher
Nature Publishing Group
Year
2012
Tongue
English
Weight
387 KB
Volume
9
Category
Article
ISSN
1552-4450

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Spectral clustering for detecting protei
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In this paper, we study spectral clustering for detecting protein complexes in PPI (protein-protein interaction) networks, focusing on two open issues: (i) constructing similarity graphs; and (ii) determining the number of clusters. First, we study four similarity graphs to construct graph Laplacian