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Detecting microcirculatory changes in blood oxygen state with steady-state free precession imaging

✍ Scribed by Rohan Dharmakumar; Xiuling Qi; Juimiin Hong; Graham A. Wright

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
424 KB
Volume
55
Category
Article
ISSN
0740-3194

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✦ Synopsis

Abstract

Recently, it has been demonstrated that oxygen‐weighted images of whole blood can be obtained with steady‐state methods. In this article, based on computational and experimental models, we investigate the potential for employing this technique to monitor oxygen changes in microcirculation. Results show that oxygen‐sensitive images of rabbit kidney and muscle may be obtained at high signal‐to‐noise ratio within a few seconds. The results also show that in steady‐state free precession imaging, in addition to the exchange mechanism that generates oxygen contrast in blood, there are additional mechanisms that provide oxygen‐sensitive contrast in microcirculation. Magn Reson Med, 2006. © 2006 Wiley‐Liss, Inc.

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