Desymmetrization of dimethyl 3-substitut
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Mónica López-Garcı́a; Ignacio Alfonso; Vicente Gotor
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Article
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2003
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Elsevier Science
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English
⚖ 157 KB
The desymmetrization of differently 3-substituted glutarates through enzymatic aminolysis and ammonolysis has been studied. The effect of the diester and nucleophile structures, the enzymatic preparation as well as the reaction conditions have been compared in terms of both the chemical yield and en