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Desymmetrization of Dimethyl 3-Substituted Glutarates Through Enzymatic Ammonolysis and Aminolysis Reactions.

✍ Scribed by Monica Lopez-Garcia; Ignacio Alfonso; Vicente Gotor


Book ID
101947200
Publisher
John Wiley and Sons
Year
2003
Weight
25 KB
Volume
34
Category
Article
ISSN
0931-7597

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Desymmetrization of dimethyl 3-substitut
✍ Mónica López-Garcı́a; Ignacio Alfonso; Vicente Gotor 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 157 KB

The desymmetrization of differently 3-substituted glutarates through enzymatic aminolysis and ammonolysis has been studied. The effect of the diester and nucleophile structures, the enzymatic preparation as well as the reaction conditions have been compared in terms of both the chemical yield and en