(R)-3-(N-Methylpyrrolidin-2-ylmethyl)-5-
โ
Ian Egle; Neil MacLean; Lidia Demchyshyn; Louise Edwards; Abdelmalik Slassi; Ash
๐
Article
๐
2003
๐
Elsevier Science
๐
English
โ 125 KB
A series of (R)-3-(N-methylpyrrolidin-2-ylmethyl)-5-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole derivatives (2) have been prepared using parallel synthesis, and their structure-activity relationship studied. High affinity human 5-HT 1B/1D (h5-HT 1B/1D ) ligands have been identified.