A clearer understanding of structure-function relationships of protein hormone-receptor systems is emerging from the increased use of molecular biology approaches. On the other hand, the introduction of rationally designed conformation constraints into peptide hormones and neurotransmitters is leadi
Designing metal–peptide models for protein structure and function
✍ Scribed by Gang Xing; Victoria J DeRose
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 250 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1367-5931
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Notwithstanding great advances in the engineering and structural analysis of globular proteins, relatively limited success has been achieved with membrane proteinsdue largely to their intrinsic high insolubility and the concomitant difficulty in obtaining crystals. Progress with de novo synthesis of
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