Design, Synthesis, and Structure–Activity Relationship Studies of 4-Quinolinyl- and 9-Acrydinylhydrazones as Potent Antimalarial Agents
✍ Scribed by Fattorusso, Caterina; Campiani, Giuseppe; Kukreja, Gagan; Persico, Marco; Butini, Stefania; Romano, Maria Pia; Altarelli, Maria; Ros, Sindu; Brindisi, Margherita; Savini, Luisa; Novellino, Ettore; Nacci, Vito; Fattorusso, Ernesto; Parapini, Silvia; Basilico, Nicoletta; Taramelli, Donatella; Yardley, Vanessa; Croft, Simon; Borriello, Marianna; Gemma, Sandra
- Book ID
- 118268776
- Publisher
- American Chemical Society
- Year
- 2008
- Tongue
- English
- Weight
- 434 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0022-2623
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A series of boron-containing benzoxaborole compounds was designed and synthesized for a structureactivity relationship investigation surrounding 7-(HOOCCH 2 CH 2 )-1,3-dihydro-1-hydroxy-2,1-benzoxaborole (1) with the goal of discovering a new antimalarial treatment. Compound 1 demonstrates the best