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Synthesis and Insight into the Structure–Activity Relationships of Chalcones as Antimalarial Agents

✍ Scribed by Tadigoppula, Narender; Korthikunta, Venkateswarlu; Gupta, Shweta; Kancharla, Papireddy; Khaliq, Tanvir; Soni, Awakash; Srivastava, Rajeev Kumar; Srivastava, Kumkum; Puri, Sunil Kumar; Raju, Kanumuri Siva Rama; Wahajuddin, ; Sijwali, Puran Singh; Kumar, Vikash; Mohammad, Imran Siddiqi


Book ID
118221834
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
889 KB
Volume
56
Category
Article
ISSN
0022-2623

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Synthesis and structure–activity relatio
✍ Yong-Kang Zhang; Jacob J. Plattner; Yvonne R. Freund; Eric E. Easom; Yasheen Zho 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 801 KB

A series of boron-containing benzoxaborole compounds was designed and synthesized for a structureactivity relationship investigation surrounding 7-(HOOCCH 2 CH 2 )-1,3-dihydro-1-hydroxy-2,1-benzoxaborole (1) with the goal of discovering a new antimalarial treatment. Compound 1 demonstrates the best