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Synthesis and Structure-Activity Relationship Studies of Pyrazole-based Heterocycles as Antitumor Agents

✍ Scribed by Ahmad M. Farag; Abdelrahman S. Mayhoub; Taha M. A. Eldebss; Abdel-Galil E. Amr; Korany A. K. Ali; Naglaa A. Abdel-Hafez; Mohamed M. Abdulla


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
881 KB
Volume
343
Category
Article
ISSN
0365-6233

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ChemInform Abstract: Synthesis and Struc
✍ Ahmad M. Farag; Abdelrahman S. Mayhoub; Taha M. A. Eldebss; Abdel-Galil E. Amr; 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 48 KB 👁 1 views

## Abstract A variety of new 1,5‐diphenylpyrazole derivatives substituted by different triazole or triazole bioisosteres at position 3 is synthesized and evaluated for their anti‐estrogenic effects and their cytotoxic properties against estrogen‐dependent tumor cell lines.