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ChemInform Abstract: Synthesis and Structure—Activity Relationship Studies of Pyrazole-Based Heterocycles as Antitumor Agents.

✍ Scribed by Ahmad M. Farag; Abdelrahman S. Mayhoub; Taha M. A. Eldebss; Abdel-Galil E. Amr; Korany A. K. Ali; Naglaa A. Abdel-Hafez; Mohamed M. Abdulla

Publisher: John Wiley and Sons
Year: 2010
Weight: 48 KB
Volume: 41
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.201047117

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✦ Synopsis

Abstract

A variety of new 1,5‐diphenylpyrazole derivatives substituted by different triazole or triazole bioisosteres at position 3 is synthesized and evaluated for their anti‐estrogenic effects and their cytotoxic properties against estrogen‐dependent tumor cell lines.

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