Design, synthesis, and pharmacological e
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Feldman, Paul L.; James, Michael K.; Brackeen, Marcus F.; Bilotta, Joanne M.; Sc
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Article
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1991
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American Chemical Society
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English
β 895 KB
In an effort to discover a potent ultrashort-acting mu opioid analgetic that is capable of metabolizing to an inactive species independent of hepatic function, several classes of 4-anilidopiperidine analgetics were synthesized and evaluated. One series of compounds displayed potent mu opioid agonist