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Design, Synthesis, and Evaluation of Biotinylated Opioid Derivatives as Novel Probes to Study Opioid Pharmacology

โœ Scribed by Li, Ya; Chase, Anna R.; Slivka, Peter F.; Baggett, Clyde T.; Zhao, Tina X.; Yin, Hang

Book ID
120016096
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
211 KB
Volume
19
Category
Article
ISSN
1043-1802

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โœ Feldman, Paul L.; James, Michael K.; Brackeen, Marcus F.; Bilotta, Joanne M.; Sc ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› American Chemical Society ๐ŸŒ English โš– 895 KB

In an effort to discover a potent ultrashort-acting mu opioid analgetic that is capable of metabolizing to an inactive species independent of hepatic function, several classes of 4-anilidopiperidine analgetics were synthesized and evaluated. One series of compounds displayed potent mu opioid agonist