Design, synthesis and pharmacological activity of substituted 1,2,3,6-tetrahydropyrimidine-5-carbonitrile
β Scribed by Ghule, Savita G.; Deshmukh, Vinayak K.; Chaudhari, Sanjay R.
- Book ID
- 123048259
- Publisher
- Elsevier
- Year
- 2013
- Tongue
- English
- Weight
- 339 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0974-6943
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## Abstract The synthesis of 6βmethylsulfanylβ2,4βdithioxoβ1,2,3,4βtetrahydropyrimidineβ5βcarbonitrile **4** is described. Compound **4** was reacted with various alkylants. The reaction with chloroacetic acid derivatives results in the formation of thieno[2,3β__d__]pyrimidines **8**. When methyl i
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