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Design, synthesis, and evaluation of novel 1-methyl-3-substituted quinazoline-2,4-dione derivatives as antimicrobial agents

โœ Scribed by Ji, Qing-Gang; Yang, Dan; Deng, Qiao; Ge, Zhi-Qiang; Yuan, Lv-Jiang


Book ID
121534790
Publisher
Springer-Verlag
Year
2013
Tongue
English
Weight
331 KB
Volume
23
Category
Article
ISSN
1054-2523

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## Abstract 3-Nitro-N-(phenylsulphonyloxy)phthalimide (IIIa) and N-(phenylsulphonyloxy)phthalimide (IIIb) were synthesised as key intermediates in good yield. Their structures were confirmed by 1H NMR and FTIR spectral data. The reaction of the key intermediates with allylamine produced 3-allyl-5-n