Synthesis and Evaluation of Novel 4-Substituted Styryl Quinazolines as Potential Antimicrobial Agents
โ Scribed by Rahul P. Modh; Amit C. Patel; Dharmesh H. Mahajan; Christophe Pannecouque; Erik De Clercq; Kishor H. Chikhalia
- Book ID
- 115550444
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 182 KB
- Volume
- 345
- Category
- Article
- ISSN
- 0365-6233
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## Abstract Quinazoline isothiocyanate 1 reacts with various nucleophiles (nitrogen nucleophiles, oxygen nucleophiles and sulphur nucleophiles) to afford heterocyclic systemes 2โ13. Also, the [4 + 2] cycloaddition reaction of 1 with phenyl isocyanate, benzylidene aryl amine and cinnamic acid deriva