Design, Synthesis, and Evaluation of a Potent Mechanism-Based Inhibitor for the TEM .beta.-Lactamase with Implications for the Enzyme Mechanism
β Scribed by Miyashita, Kazuyuki; Massova, Irina; Taibi, Pascale; Mobashery, Shahriar
- Book ID
- 121465014
- Publisher
- American Chemical Society
- Year
- 1995
- Tongue
- English
- Weight
- 592 KB
- Volume
- 117
- Category
- Article
- ISSN
- 0002-7863
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Design, Synthesis, and Evaluation of the First Mechanism-Based Inhibitor of Glucosamine 6-Phosphate Synthase. -The first example of the title inhibitor, the compound (I), a glutamine derivative bearing a latent electrophilic function, is prepared starting from suitably protected glutamine. (I) is st
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