Synthesis of Sequence-Selective C8-Linked Pyrrolo(2,1-c)(1,4) benzodiazepine DNA Interstrand Cross-Linking Agents. -In order to construct the key A-ring fragments (VI), a versatile convergent approach is developed to join two units of vanillic acid (I) with ฮฑ,ฯ-dihaloalkanes (II). The "amino-thioac
โฆ LIBER โฆ
Design, Synthesis, and Evaluation of a Novel Sequence-Selective Epoxide-Containing DNA Cross-Linking Agent Based on the Pyrrolo[2,1- c ][1,4]benzodiazepine System
โ Scribed by Wilson, Stuart C.; Howard, Philip W.; Forrow, Stephen M.; Hartley, John A.; Adams, Lesley J.; Jenkins, Terence C.; Kelland, Lloyd R.; Thurston, David E.
- Book ID
- 118010116
- Publisher
- American Chemical Society
- Year
- 1999
- Tongue
- English
- Weight
- 293 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0022-2623
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