ChemInform Abstract: Synthesis of Sequen
✍
D. E. THURSTON; D. S. BOSE; A. S. THOMPSON; P. W. HOWARD; A. LEONI; S. J. CROKER
📂
Article
📅
2010
🏛
John Wiley and Sons
⚖ 38 KB
👁 1 views
Synthesis of Sequence-Selective C8-Linked Pyrrolo(2,1-c)(1,4) benzodiazepine DNA Interstrand Cross-Linking Agents. -In order to construct the key A-ring fragments (VI), a versatile convergent approach is developed to join two units of vanillic acid (I) with α,ω-dihaloalkanes (II). The "amino-thioac