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Design, Synthesis, and Evaluation of a Depsipeptide Mimic of Tendamistat

โœ Scribed by Sefler, Andrea M.; Kozlowski, Marisa C.; Guo, Tao; Bartlett, Paul A.


Book ID
120328857
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
549 KB
Volume
62
Category
Article
ISSN
0022-3263

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## Abstract On the basis of the total synthesis of obyanamide, 20 analogues of this marine cyclic depsipeptide have been synthesized by (i) preparation of the tripeptide fragments in the western hemisphere using Z/OtBu protocol; (ii) preparation of the dipeptide fragments in the eastern hemisphere