An efficient and scalable synthesis of (
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Aihua Wang; Yan Zhang; Songfeng Lu; William V. Murray; Gee-Hong Kuo
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Article
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2010
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Journal of Heterocyclic Chemistry
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English
⚖ 140 KB
## Abstract magnified image An efficient and scalable synthesis of the potent CETP inhibitor, (2__R__,α__S__)‐3,4‐dihydro‐2‐[3‐(1,1,2,2‐tetrafluoroethoxy)phenyl]‐5‐[3‐(trifluoromethoxy)phenyl]‐α‐(trifluoromethyl)‐1(2__H__)‐quinolineethanol 1, is described. One of the important intermediates, tetrah