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Design, Synthesis and Antimalarial Activity of Trifluoromethylartemisinin–Mefloquine Dual Molecules

✍ Scribed by Fabienne Grellepois; Philippe Grellier; Danièle Bonnet-Delpon; Jean-Pierre Bégué


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
110 KB
Volume
6
Category
Article
ISSN
1439-4227

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ChemInform Abstract: Design, Synthesis,
✍ J. N. CUMMING; D. WANG; S. B. PARK; T. A. SHAPIRO; G. H. POSNER 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 37 KB 👁 1 views

Alcohol Analogues of the Antimalarial Artemisinin. -A series of the title compounds such as (VIII)-(XI) is synthesized and used in the preparation of derivatives such as (XIII). These products are potent antimalarials with up to 140% of the efficacy of the natural artemisinin. -(CUMMING,