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Design of two-helix motifs in peptides: crystal structure of a system of linked helices of opposite chirality and a model helix–linker peptide

✍ Scribed by Isabella L Karle; Arindam Banerjee; Padmanabhan Balaram


Book ID
114382629
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
101 KB
Volume
2
Category
Article
ISSN
1359-0278

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Design, synthesis, and crystal structure
✍ Darshan Ranganathan; Sunita Kurur; Isabella L. Karle 📂 Article 📅 2000 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 223 KB 👁 2 views

Norbornene-supported bis-helical peptides with the general structure NBE(Aib n ) 2 (NBE: 2,3-trans-norbornene dicarbonyl unit; Aib: ␣,␣Ј-dimethyl glycine unit; n ϭ 4,5) have been synthesized and examined for self-assembly preferences in the solid state. An x-ray study has revealed a phenomenon of Ja