Design, synthesis, and conformation of a model peptide of endothelin with cystine-stabilized α-helix motif

Conformational study of endothelins and

Conformational study of endothelins and sarafotoxins with the cystine-stabilized helical motif by means of CD spectra

✍ Haruhiko Tamaoki; Yoshimasa Kyogoku; Kiichiro Nakajima; Shumpei Sakakibara; Mits 📂 Article 📅 1992 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 321 KB

A series of CD measurements were carried out on members of peptides in the endothelin and sarafotoxin families. The helical structures taken by these peptides containing the helical motif with the sequences of Cys-X-X-X-Cys and Cys-X-Cys [ Y. Kobayashi et al. ( 1991) Neurochemistry International Vo

Design, Synthesis and Structural Investi

Design, Synthesis and Structural Investigations of a β-Peptide Forming a 314-Helix Stabilized by Electrostatic Interactions

✍ Magnus Rueping; Yogesh R. Mahajan; Bernhard Jaun; Dieter Seebach 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 374 KB 👁 1 views

## Abstract Two different strategies have been employed for the synthesis of Fmoc‐protected β^3^‐homoarginine; the Arndt–Eistert homologation of α‐arginine and the guanidinylation of β^3^‐homoornithine. Solid‐phase β‐peptide synthesis was used for the preparation of β‐heptapeptide **1**, which was

Design and synthesis of 3α-helix peptide

Design and synthesis of 3α-helix peptides forming a cavity for a fluorescent ligand

✍ Ikuo Obataya; Seiji Sakamoto; Akihiko Ueno; Hisakazu Mihara 📂 Article 📅 2001 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 134 KB 👁 1 views

As a model of receptor protein, a series of 3␣-helix bundle peptides constructed on a template peptide were designed so as to possess a hydrophobic cavity. The size of cavity was modulated by simple replacements of Leu residues to Ala residues in the hydrophobic core. Binding abilities to 8-anilino-

A Left-Handed 9-Helix in γ-Peptides: Syn

A Left-Handed 9-Helix in γ-Peptides: Synthesis and Conformational Studies of Oligomers with Dipeptide Repeats of C-Linked Carbo-γ4-amino Acids and γ-Aminobutyric Acid

✍ Gangavaram V. M. Sharma; Pagadala Jayaprakash; Kongari Narsimulu; Ampapathi Ravi 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 237 KB 👁 1 views

The design of nonnatural oligomers that form diversified secondary structures is an active area of research. [1] An extensive search of the b-peptide class of foldamers has provided several new secondary structures, while the gpeptides, despite the possibility of having and traversing a larger confo

A Left-Handed 9-Helix in γ-Peptides: Syn

A Left-Handed 9-Helix in γ-Peptides: Synthesis and Conformational Studies of Oligomers with Dipeptide Repeats of C-Linked Carbo-γ4-amino Acids and γ-Aminobutyric Acid

✍ Gangavaram V. M. Sharma; Pagadala Jayaprakash; Kongari Narsimulu; Ampapathi Ravi 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 236 KB 👁 1 views

The design of nonnatural oligomers that form diversified secondary structures is an active area of research. [1] An extensive search of the b-peptide class of foldamers has provided several new secondary structures, while the gpeptides, despite the possibility of having and traversing a larger confo