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Conformational study of endothelins and sarafotoxins with the cystine-stabilized helical motif by means of CD spectra

✍ Scribed by Haruhiko Tamaoki; Yoshimasa Kyogoku; Kiichiro Nakajima; Shumpei Sakakibara; Mitsuo Hayashi; Yuji Kobayashi


Publisher
Wiley (John Wiley & Sons)
Year
1992
Tongue
English
Weight
321 KB
Volume
32
Category
Article
ISSN
0006-3525

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✦ Synopsis


A series of CD measurements were carried out on members of peptides in the endothelin and sarafotoxin families. The helical structures taken by these peptides containing the helical motif with the sequences of Cys-X-X-X-Cys and Cys-X-Cys [ Y. Kobayashi et al.

( 1991) Neurochemistry International Vol. 18, pp. 525-5341 are classified into three groups: a group of structures of ET-1, ET-2 and vasoactive intestinal contractor (VIC), a group of sarafotoxin, and a group of ET-3.