✦ LIBER ✦

Design of Inhibitors of the MurF Enzyme of Streptococcus pneumoniae Using Docking, 3D-QSAR, and de Novo Design.

✍ Scribed by Santosh A. Khedkar; Alpeshkumar K. Malde; Evans C. Coutinho

Publisher: John Wiley and Sons
Year: 2007
Weight: 11 KB
Volume: 38
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200749229

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Application of 3D-QSAR in the Rational D

Application of 3D-QSAR in the Rational Design of Receptor Ligands and Enzyme Inhibitors

✍ Marco Mor; Silvia Rivara; Alessio Lodola; Simone Lorenzi; Fabrizio Bordi; Pier V 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 425 KB 👁 1 views

3D QSAR Selectivity Analyses of Carbonic

3D QSAR Selectivity Analyses of Carbonic Anhydrase Inhibitors: Insights for the Design of Isozyme Selective Inhibitors.

✍ Alexander Weber; Markus Boehm; Claudiu T. Supuran; Andrea Scozzafava; Christoph 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 11 KB

Molecular docking of enzyme inhibitors :

Molecular docking of enzyme inhibitors : A COMPUTATIONAL TOOL FOR STRUCTURE-BASED DRUG DESIGN

✍ Aleksandra Rudnitskaya; Béla Török; Marianna Török 📂 Article 📅 2010 🏛 The American Society for Biochemistry and Molecula 🌐 English ⚖ 175 KB 👁 2 views

De Novo Design, Synthesis, and In Vitro

De Novo Design, Synthesis, and In Vitro Evaluation of a New Class of Nonpeptidic Inhibitors of the Malarial Enzyme Plasmepsin II

✍ David A. Carcache; Simone R. Hörtner; Andreas Bertogg; Christoph Binkert; Daniel 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 152 KB 👁 2 views

Malaria, a life-threatening disease caused by parasites of the genus Plasmodium, affects 500 million people annually, of which more than one million die. [1] The emergence of multi-drugresistant strains of Plasmodium falciparum, the parasite that causes the deadliest form of malaria, exacerbates the

ChemInform Abstract: The De Novo Design

ChemInform Abstract: The De Novo Design and Synthesis of Cyclic Urea Inhibitors of Factor Xa: Optimization of the S4 Ligand.

✍ Robert A. Galemmo Jr.; et al. et al. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 30 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

ChemInform Abstract: The DE Novo Design

ChemInform Abstract: The DE Novo Design and Synthesis of Cyclic Urea Inhibitors of Factor Xa: Initial SAR Studies.

✍ R. A. JUN. GALEMMO; T. P. MADUSKUIE; C. DOMINGUEZ; K. A. ROSSI; R. M. KNABB; R. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 30 KB 👁 1 views

The DE Novo Design and Synthesis of Cyclic Urea Inhibitors of Factor Xa: Initial SAR Studies. -A series of cyclic ureas is prepared and tested as inhibitors of the blood coagulation protein factor Xa. Molecular modelling calculations are performed to study the docking of the compounds to the factor