𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Design Issues for the Michaelis–Menten Model

✍ Scribed by J. LÓPEZ-FIDALGO; WENG KEE WONG

Book ID
102613677
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
174 KB
Volume
215
Category
Article
ISSN
0022-5193

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✦ Synopsis

We discuss design issues for the Michaelis}Menten model and use geometrical arguments to "nd optimal designs for estimating a subset of the model parameters, or a linear combination of the parameters. We propose multiple-objective optimal designs when the parameters have di!erent levels of interest to the researcher. In addition, we compare six commonly used sequence designs in the biological sciences for estimating parameters and, propose optimal choices for the parameters for geometric designs using closed-form e$ciency formulas.

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