Design and synthesis of novel nucleobase-based barbiturate derivatives as potential anticancer agents
✍ Scribed by Bhaveshkumar D. Dhorajiya, Ahmed S. Ibrahim…
- Book ID
- 120908822
- Publisher
- Springer-Verlag
- Year
- 2013
- Tongue
- English
- Weight
- 426 KB
- Volume
- 23
- Category
- Article
- ISSN
- 1054-2523
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The simple anthracycline analogues 3a-e were synthesized as potential anticancer agents. Anodic oxidation of the phenol derivative 4, phthalide anion annelation ofp-quinone monoacetals 5 and selective attachment of the side chain were the three key steps towards these target compounds.