Design and synthesis of hapten to induce phospholipase A2-like catalytic antibody
β Scribed by Shigeki Isomura; Mitsumasa Haruna; Kazuo Ito
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 226 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0960-894X
No coin nor oath required. For personal study only.
β¦ Synopsis
Haptens la and I b, transition-state analogs inducing phospholipase Az-like catalytic antibody, were synthesized. Hapten la inhibited hydrolysis of the sn-2 ester of phospholipid.
π SIMILAR VOLUMES
An efficient synthetic route to both cis-and tram-fused racemic 4a,6-dimethyloctahydroquinoline-N-oxides has been developed. These species were employed as haptens to elicit catalytic antibodies capable of controlling the corresponding bicyclic hydrocarbon formation from linear quasi-triisoprenoid s
Syntheses of Octahydroquinoline-N-oxides: Haptens Designed to Elicit Catalytic Antibodies that Control a Terpenoid-Like Cascade Cyclization. -The title compounds are prepared starting from cis-and trans-fused perhydroquinolines, e.g. (VIII). In this context an improved synthesis of diastereomeric q