๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Derivatized oxopiperazine rings from amino acids

โœ Scribed by Ulhas Bhatt; Nazim Mohamed; George Just; Edward Roberts

Book ID
104257088
Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
208 KB
Volume
38
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

โœฆ Synopsis

Two routes for the synthesis of derivatized oxopiperazines, which may act as constrained peptide mimics, are reported The syntheses employ reductive amination and sulfonamide approaches for generating N-allylic amino acid ester derivatives and utilizing them for assembling the ring systems. An aspartame analog was prepared using this methodology.

๐Ÿ“œ SIMILAR VOLUMES

ChemInform Abstract: Derivatized Oxopipe
ChemInform Abstract: Derivatized Oxopiperazine Rings from Amino Acids.
โœ U. BHATT; N. MOHAMED; G. JUST; E. ROBERTS ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 31 KB ๐Ÿ‘ 1 views

Derivatized Oxopiperazine Rings from Amino Acids. -Two dipeptide mimics (VII) and (XIV) are synthesized by employment of reductive amination and sulfonamide approaches for the preparation of allylic derivatives (IV) and (XIII), which are further utilized for assembling the ring systems, as is shown