𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Derivatization of Double Bonds Investigated by Matrix-assisted Laser Desorption/Ionization Mass Spectrometry

✍ Scribed by G. Kühn; St. Weidner; R. Decker; A. Holländer

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
133 KB
Volume
11
Category
Article
ISSN
0951-4198

No coin nor oath required. For personal study only.

✦ Synopsis

Hexatriacontane (C 36 ) was exposed to vacuum ultraviolet radiation. The formation of double bonds was investigated by derivatization, i.e. these olefinic structures were transformed by epoxidation in order to determine their number in the molecule. The extent of the reaction was determined by means of matrix-assisted laser desorption/ionization mass spectrometry. In order to confirm the results a model compound (squalene) containing six double bonds was also investigated. As a result of the derivatization an easier ionization of functionalized substances caused by an increase in their polarity was found. As a result, the sample preparation was changed and the use of silver salts for a better ionization of non-polar alkanes could be avoided.

📜 SIMILAR VOLUMES

Chemical End-group Derivatization of Pol
Chemical End-group Derivatization of Poly(ethyleneglycol)—Investigation by Matrix-assisted Laser Desorption/Ionization Mass Spectrometry
✍ St. Weidner; G. Kühn 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 392 KB 👁 1 views

The hydroxy end-groups of poly(ethyleneglyco1) polymers PEG lo00 and 4000) were derivatized by etherification using methyl, ethyl and triphenylmethyl (trityl) halogenides. During the derivatization the molecular mass distribution of monoand disubstituted polymers as well as unsubstituted polymers co

Mass Spectrometry of Low Molecular Mass
Mass Spectrometry of Low Molecular Mass Solids by Matrix-assisted Laser Desorption/Ionization
✍ Goheen, Steven C.; Wahl, Karen L.; Campbell, James A.; Hess, Wayne P. 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 325 KB 👁 2 views

Matrix-assisted laser desorption/ionization combined with time-of-Ñight mass spectrometry (MALDI/TOF-MS) was used for the analysis of low molecular mass compounds. Three classes of molecules were studied : organic acids, salts of oxyanions and amine-based chelating compounds. Mass spectra from sampl

Quantitative Analysis of Oligonucleotide
Quantitative Analysis of Oligonucleotides by Matrix-assisted Laser Desorption/Ionization Mass Spectrometry
✍ Bernd A. Bruenner; Tai-Tung Yip; T. William Hutchens 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 434 KB 👁 2 views

Quantitative aspects of oligonucleotide analysis by matrix-assisted laser desorption/iotion (MALDI) mass spectrometry remain largely unexplored relative to the efforts that have been devoted to quantitative peptide and protein analysis. The successful quantitation of these other biopolymers coupled

Structural characterization of polyoxyme
Structural characterization of polyoxymethylenes by matrix-assisted laser desorption/ionization mass spectrometry
✍ Hiroaki Sato; Hajime Ohtani; Shin Tsuge; Noriyuki Hayashi; Koichi Katoh; Eiji Ma 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 161 KB 👁 2 views

Several polyoxymethylene (POM) model compounds with relatively low molecular weights were characterized by matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) using dithranol matrix, 1,1,1,3,3,3-hexafluoro-2-propanol solvent for matrix/analyte solution, and sodium iodide as cati

Chemical reactivity in matrix-assisted l
Chemical reactivity in matrix-assisted laser desorption/ionization mass spectrometry
✍ C. Enjalbal; B. Sauvagnat; F. Lamaty; R. Lazaro; J. Martinez; P. Mouchet; F. Rou 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 139 KB 👁 2 views

During the control of a multistep organic synthesis on a soluble polymer (PEG) by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry, a chemical reactivity was encountered when the matrix was acidic, for the samples where the amino moiety of the anchored compounds was protected as

Differentiation of enantiomers using mat
Differentiation of enantiomers using matrix-assisted laser desorption/ionization mass spectrometry
✍ M. P. So; T. S. M. Wan; T.-W. Dominic Chan 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 54 KB 👁 2 views

Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) has successfully been used to differentiate pseudo-enantiomeric (isotopically labelled) amino acids by using cyclodextrin as complexing host. By using different pseudo-enantiomeric mixtures (i.e. R Dn S; and R S Dn ), it has be