Derivatives of perhydrofuro[2,3-c]pyridin-2-one
✍ Scribed by Ronald F. Borne; Hassan Y. Aboul-Enein
- Book ID
- 112126229
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1980
- Tongue
- English
- Weight
- 235 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0022-152X
No coin nor oath required. For personal study only.
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## Abstract Es wird die Synthese von Furo[3,2‐__c__]pyridin‐3‐olen **3** aus 4‐Hydroxy‐3‐pyridincarbonsäureestern **2** beschrieben. Hydrolyse der Estergruppe an C‐2 von **3e** führt unter Decarboxylierung zum Furo[3,2‐__c__]pyridin‐3(2__H__)‐on **4b** (R^4^ = H), aus dem mit Aldehyden die ungesätt
## Abstract 2-[3-(Trifluoromethyl)phenyl]-4,5-dihydrofuro[3,2-c]pyridin-4-one (I) was prepared by a three-step synthesis. Its reaction with phosphorus sulfide rendered thione II which was methylated to 2-[3-(Trifluoromethyl)phenyl]-4-methylsulfanylfuro[3,2-c]pyridine (III). 5-Methyl-2-[3-(trifluoro