## Abstract 2-[3-(Trifluoromethyl)phenyl]-4,5-dihydrofuro[3,2-c]pyridin-4-one (I) was prepared by a three-step synthesis. Its reaction with phosphorus sulfide rendered thione II which was methylated to 2-[3-(Trifluoromethyl)phenyl]-4-methylsulfanylfuro[3,2-c]pyridine (III). 5-Methyl-2-[3-(trifluoro
β¦ LIBER β¦
Synthesis of furo[2,3-c]pyridine derivatives
β Scribed by Mertes, Mathias P.; Borne, Ronald F.; Hare, Larry E.
- Book ID
- 127220624
- Publisher
- American Chemical Society
- Year
- 1968
- Tongue
- English
- Weight
- 700 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0022-3263
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## Abstract Chlorination of the __N__βoxides of furo[2,3β__b__]β 1a, β[2,3β__c__]β 1b and β[3,2βc]pyridine 1c with phosphorus oxychloride afforded compounds substituted normally at the Ξ±β or Ξ»βposition to the ring nitrogen, 2a, 2β²a, 2b, 2c, 2β²c and 2β²c, and in addition, in the case of 1b, compounds
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