In mouse mammary tumorigenesis, p53 mutations facilitate tumorigenesis in concert with other oncogenic alterations. Ionizing radiation enhances tumorigenesis in preneoplastic mammary outgrowth lines and induces p53-dependent apoptosis. We asked if normal p53 function modulates radiation-induced tumo
Deregulated cyclin E promotes p53 loss of heterozygosity and tumorigenesis in the mouse mammary gland
β Scribed by Smith, A P L; Henze, M; Lee, J A; Osborn, K G; Keck, J M; Tedesco, D; Bortner, D M; Rosenberg, M P; Reed, S I
- Book ID
- 110070730
- Publisher
- Nature Publishing Group
- Year
- 2006
- Tongue
- English
- Weight
- 430 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0950-9232
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