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Depletion of mitochondrial fission factor DRP1 causes increased apoptosis in human colon cancer cells

✍ Scribed by Akane Inoue-Yamauchi; Hideaki Oda


Book ID
116303265
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
689 KB
Volume
421
Category
Article
ISSN
0006-291X

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## Abstract Lactate production from glucose even in the presence of oxygen is a characteristic of cancer cell metabolism and an important feature for tumor progression. Here, we describe that an increased uptake of lactate into mitochondria of HT‐29 human colon cancer cells by treatment of cells wi