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Increased mitochondrial palmitoylcarnitine/carnitine countertransport by flavone causes oxidative stress and apoptosis in colon cancer cells

โœ Scribed by U. Wenzel; A. Nickel; H. Daniel


Publisher
Springer
Year
2005
Tongue
English
Weight
907 KB
Volume
62
Category
Article
ISSN
1420-682X

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## Abstract Lactate production from glucose even in the presence of oxygen is a characteristic of cancer cell metabolism and an important feature for tumor progression. Here, we describe that an increased uptake of lactate into mitochondria of HTโ€29 human colon cancer cells by treatment of cells wi