Dephosphonylation of β-Carbonyl Phosphonates
✍ Scribed by Lee, Shi Yong; Lee, Chi-Wan; Oh, Dong Young
- Book ID
- 126224030
- Publisher
- American Chemical Society
- Year
- 1999
- Tongue
- English
- Weight
- 77 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0022-3263
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The conversion of four 5'-O-(4,4'-dimethoxytrityl)-2'-deoxyribonucleoside 3'-H-phosphonates 1 (B---4, 5, 6 and 7) into their partially-protected nucleoside precursors 3 (B--4, 5, 6 and 7, respectively) in good isolated yields is described. The procedure used is also suitable for the dephosphonylatio
Alkylation of [5-keto phosphonates is performed by teatment of 15-keto phosphonates with n-BuLi, followed by addition of alkyl halides. The acquired c~fully substituted 13-keto phosphonates are dephosphonylated by treatment of the lithium enolates with LiAIH4, followed by quenching with aqueous H2SO