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Dephosphonylation of β-Carbonyl Phosphonates

✍ Scribed by Lee, Shi Yong; Lee, Chi-Wan; Oh, Dong Young


Book ID
126224030
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
77 KB
Volume
64
Category
Article
ISSN
0022-3263

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📜 SIMILAR VOLUMES


Dephosphonylation of protected deoxynucl
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The conversion of four 5'-O-(4,4'-dimethoxytrityl)-2'-deoxyribonucleoside 3'-H-phosphonates 1 (B---4, 5, 6 and 7) into their partially-protected nucleoside precursors 3 (B--4, 5, 6 and 7, respectively) in good isolated yields is described. The procedure used is also suitable for the dephosphonylatio

Dephosphonylation of α-fully substituted
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Alkylation of [5-keto phosphonates is performed by teatment of 15-keto phosphonates with n-BuLi, followed by addition of alkyl halides. The acquired c~fully substituted 13-keto phosphonates are dephosphonylated by treatment of the lithium enolates with LiAIH4, followed by quenching with aqueous H2SO