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Deoxycholic (DOC) acid-induced expression of cyclooxygenase-2 (COX-2) in human colonic fibroblasts

โœ Scribed by Shazia Rafiq; Yingting Zhu; Peter Lance


Book ID
119429700
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
189 KB
Volume
120
Category
Article
ISSN
0016-5085

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Cyclooxygenase (COX)-2 is a possible molecular target for suppression of colon carcinogenesis by non-steroidal antiinflammatory drugs (NSAIDs). However, the expression of COX-2 in human colonic tumors during the adenomacarcinoma sequence has not been elucidated. In the present study, we examined imm