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Dendrimers conjugates for colonic delivery of 5-aminosalicylic acid

✍ Scribed by Ruedeekorn Wiwattanapatapee; Luelak Lomlim; Krisanee Saramunee

Book ID
114162153
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
470 KB
Volume
88
Category
Article
ISSN
0168-3659

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✍ Mohammad Reza Saboktakin; Roya M. Tabatabaie; Abel Maharramov; Mohammad Ali Rama πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 149 KB

The main aim of this research was to develop and evaluate a multiparticulate system of Ac-poly(amidoamine)(PAMAM)(G4)-chitosan (CS) hydrogels exploiting pH-sensitive and specific biodegradability properties for colon-targeted delivery of 5-aminosalicylic acid (5-ASA). All formulations were evaluated