The human hepatoblastoma-derived cell line HB6 I I secretes hepatitis-B surface antigen (HBsAg) and hepatitis-B e antigen (HBeAg) into the medium. Hepatitis-B-virus(HBV) DNA integrated into the cellular genome was found to be hypermethylated. When the cells were treated with 5-azacytidine for 3 days
β¦ LIBER β¦
Demethylation by 5-Azacytidine Results in the Expression of Hepatitis B Virus Surface Antigen in Transgenic Mice
β Scribed by Araki, Kimi ;Miyazaki, Jun-ichi ;Tsurimoto, Toshiki ;Inomoto, Takeaki ;Iwanaga, Tomohisa ;Matsubara, Kenichi ;Yamamura, Ken-ichi
- Book ID
- 108578950
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1989
- Tongue
- English
- Weight
- 249 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0910-5050
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