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Maternal inhibition of hepatitis B surface antigen gene expression in transgenic mice correlates with de novo methylation

✍ Scribed by Hadchouel, Michelle; Farza, Hend; Simon, Dominique; Tiollais, Pierre; Pourcel, Christine

Book ID
109750696
Publisher
Nature Publishing Group
Year
1987
Tongue
English
Weight
439 KB
Volume
329
Category
Article
ISSN
0028-0836

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## Abstract We previously showed that hepatitis B surface antigen (HBsAg)‐producing transgenic mice were more sensitive to hepatocarcinogens than their normal littermates were. We have now investigated the regulation of hepatitis B virus (HBV) gene expression in carcinogen‐induced liver tumors of H