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Delivery of radioiodinated antisense oligonucleotides in long circulating liposomes in vivo

โœ Scribed by Chao Ma; Jizheng Lin; Jiawei Xie; Guoming Wang; Zuo Shuyao

Book ID
102173737
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
491 KB
Volume
113
Category
Article
ISSN
1438-7697

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โœ Lloyd G. Tillman; Richard S. Geary; Gregory E. Hardee ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 206 KB

Treatment of systemic disease with phosphorothioate antisense oligonucleotides (PS ASOs) has been accomplished using local or parenteral routes of administration to date. This report describes, for the first time, the effective oral delivery of a second generation oligonucleotide where significant m