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Deletion of mtDNA disrupts mitochondrial function and structure, but not biogenesis

✍ Scribed by Ekhson Holmuhamedov; Arshad Jahangir; Martin Bienengraeber; Lionel D Lewis; Andre Terzic


Book ID
117798522
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
582 KB
Volume
3
Category
Article
ISSN
1567-7249

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We have shown that microsatellite instability (MSI) occurs in mitochondrial DNA (mtDNA) of colorectal carcinomas. To determine whether such mitochondrial microsatellite instability (mtMSI) is associated with certain forms of mitochondrial gene alterations, we extended the screening in the same serie