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Delayed gene therapy of glial cell line-derived neurotrophic factor is efficacious in a rat model of Parkinson's disease

✍ Scribed by Jie-Sheng Zheng; Ling-Ling Tang; Shu-Sen Zheng; Ren-Ya Zhan; Yong-Qing Zhou; John Goudreau; David Kaufman; Alex F. Chen

Book ID
116753132
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
294 KB
Volume
134
Category
Article
ISSN
0169-328X

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Parkinson's disease (PD) is a progressive neurodegenerative disorder that affects approximately 1,000,000 Americans. The cause of the disease remains unknown. The histopathological hallmarks of the disease are dopaminergic striatal insufficiency secondary to a loss of dopaminergic neurons in the sub