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Mutation Analysis of the Glial Cell Line-Derived Neurotrophic Factor Gene in Parkinson's Disease

✍ Scribed by Kirmo Wartiovaara; Marjo Hytönen; Minna Vuori; Lars Paulin; Juha Rinne; Hannu Sariola

Book ID
115606819
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
46 KB
Volume
152
Category
Article
ISSN
0014-4886

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Parkinson's disease (PD) is a progressive neurodegenerative disorder that affects approximately 1,000,000 Americans. The cause of the disease remains unknown. The histopathological hallmarks of the disease are dopaminergic striatal insufficiency secondary to a loss of dopaminergic neurons in the sub