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Depletion of glial cell line-derived neurotrophic factor in substantia nigra neurons of Parkinson's disease brain

✍ Scribed by Neelima B Chauhan; George J Siegel; John M Lee

Book ID: 117593348
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 795 KB
Volume: 21
Category: Article
ISSN: 0891-0618
DOI: 10.1016/s0891-0618(01)00115-6

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Parkinson's disease (PD) is a progressive neurodegenerative disorder that affects approximately 1,000,000 Americans. The cause of the disease remains unknown. The histopathological hallmarks of the disease are dopaminergic striatal insufficiency secondary to a loss of dopaminergic neurons in the sub